Mutations

This lesson covers:

  1. What 'DNA mutations' are 
  2. How mutations can arise 
  3. The possible consequences of mutations
  4. You do not need to know about insertion or deletion mutations, which is why the video finishes early, but feel free to watch on if you're interested 

What is a mutation?

A change in the way an organism looks

A change in the base sequence of DNA 

A change to the structure of an organisms cells

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True of false? Mutations can occur spontaneously in our cells, but certain factors can increase the risk.

True

False

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Which of the following can increase the risk of mutations?

(Select all that apply)

Carcinogens like those found in cigarette smoke 

A balanced diet

Regular exercise 

Ionising radiation such as x-rays and gamma rays

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Will exposure to ionising radiation always cause a mutation?

Yes

No

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one / two / three / four / five


A triplet, or a codon, is a set of bases which codes for amino acid.

three
one

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A mutation to one of the bases in DNA can change the that a triplet (codon) codes for. 

amino
acid

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What is the most likely result of a genetic mutation?

A significant disadvantage to the organism 

A significant advantage to the organism 

No significant change to the organism 

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Most mutations occur in _______________ .

Non-coding DNA

Coding DNA

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Non-coding DNA often controls the expression of coding DNA.


What does it mean for a gene to be expressed?

It's turned on, so the proteins it codes for will be produced 

It's turned off, so the proteins it codes for will not be produced 

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What happens in a substitution mutation?

One base in the sequence is replaced with a different base 

An extra base is added into the sequence 

A base is deleted from the sequence 

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Enzymes are proteins that speed up the rate of chemical reactions.


Describe how a change of one of the bases in the gene for an enzyme could affect the functioning of that enzyme. 

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