Microbiology

This practical lesson covers:

  1. The effect of antiseptic or antibiotics on bacterial growth using agar plates and measuring zones of inhibition

Investigating the effect of antiseptic or antibiotics on bacterial growth

Aim:

  1. To investigate the effect of antiseptics or antibiotics on bacterial growth using agar plates and measuring zones of inhibition. 

Background information:

Antiseptics and antibiotics inhibit or kill bacteria, which can be quantitatively assessed using agar diffusion tests. This practical involves applying these agents to agar plates inoculated with bacteria and measuring the zones of inhibition around filter paper discs.

Variables:

  1. Independent variable - Type of antiseptic or antibiotic applied.
  2. Dependent variable - Diameter of zone of inhibition.
  3. Control variables - Temperature of incubation, concentration of antiseptics/antibiotics, duration of incubation.

What is the purpose of dividing the agar plate into three sections?

to prevent anaerobic conditions

to compare the effect of different antiseptics

to measure the diameter of the clear zone

to create a control group

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Why is it important to wash hands with antibacterial soap before handling the filter paper discs?

to sterilise the filter paper discs

to ensure accurate measurement of the clear zone diameter

to remove any potential contaminants from the hands

to prevent the growth of harmful bacteria

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What is the purpose of incubating the agar plate at 25°C for 48 hours?

to measure the diameter of the clear zone

to prevent anaerobic conditions

to allow bacteria to grow and form colonies

to compare the effect of different antiseptics

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What is the purpose of spraying the work surface with disinfectant?

to prevent the growth of harmful bacteria

to sterilise the agar plate

to clean and remove potential contaminants

to measure the diameter of the clear zone

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