Welcome to the Quiz!
This quiz contains 8 questions from a mix of 1 subtopics.
Which of the following improvements were made to Sanger sequencing techniques?
(Select all that apply)
substitution of fluorescent tags with radioactive labels
enhancements in scaling up
introduction of capillary sequencing
increased speed but higher costs
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What was the primary goal of the Human Genome Project?
to reduce the cost of DNA sequencing
to introduce next-generation sequencing
to develop new DNA sequencing techniques
to map the entire human genome and share the data publicly
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In a common DNA sequencing approach, what role do terminator bases play?
they detect the fluorescent colours of bases
they stop DNA synthesis when incorporated
they separate DNA fragments
they copy DNA fragments
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Which technique is used to separate DNA fragments based on their length?
electrophoresis
DNA replication
laser detection
computer software analysis
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How has next-generation sequencing impacted the speed of DNA sequencing?
it has slightly increased the speed of sequencing
it has made sequencing slower but more accurate
it has exponentially increased the speed of sequencing
it has not significantly affected the speed of sequencing
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Which of the following statements about next-generation sequencing is true?
it has slowed down the sequencing process
it has made it possible to sequence the genomes of more organisms
it has made sequencing more expensive
it has made sequencing less accurate
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Which of the following is NOT a fundamental principle shared by modern DNA sequencing methods?
DNA fragmentation
sorting DNA fragments by size
reconstruction of the full genome using radioactive labelling
using primers, DNA polymerase, standard nucleotide bases, and terminator bases
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What is the primary role of computer software in a common DNA sequencing approach?
to sort fragments by size
to copy DNA fragments
to fragment DNA
to reconstruct the full genome by identifying overlapping areas
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