What are enantiomers?



Enantiomers are optical isomers that are non-superimposable mirror images about a chiral centre.


For example, the enantiomers of lactic acid are shown below.

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Explain what is meant by a chiral centre.

A chiral centre is a carbon atom in a molecule bonded to four different atoms or groups.


Chiral centres are often indicated on formulae by an asterisk (*).

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How do enantiomers differ in their interaction with plane-polarised light?

Enantiomers rotate plane-polarised light in opposite directions; one rotates it clockwise, and the other rotates it anti-clockwise.

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What does it mean for a molecule to be optically active?

A molecule is considered optically active if it has the ability to rotate the plane of polarised light due to its chiral structure.

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What is meant by the term racemic mixture?

A racemic mixture is an equal mixture of two enantiomers of a chiral compound.


A racemic mixture is also called a racemate.

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Why are racemic mixtures optically inactive?

Racemic mixtures are optically inactive because the rotations caused by the two enantiomers cancel each other out.


Since there are equal amounts rotating clockwise and anti-clockwise, the net rotation is zero and no optical activity is observed.

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What is optical isomerism?

Optical isomerism is a type of stereoisomerism where isomers have the same structural formula but different arrangements of atoms in space.

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How can optical isomers be distinguished?

Optical isomers can be distinguished by their ability to rotate plane-polarised light in opposite directions. One optical isomer rotates it clockwise, while the other rotates it anti-clockwise.

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