How do specific defence mechanisms differ from non-specific defence mechanisms?

Specific defence mechanisms are slower than non-specific defences, but they produce a unique response for each type of pathogen and provide long-term immunity.

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Where in the body do T cells mature?

T cells mature in the thymus gland. 

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Where in the body do B cells mature?

B cells mature in the bone marrow.

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Which part of the specific immune response involves T lymphocytes?

T lymphocytes, or T cells, are involved in the cellular response of the specific immune response.

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Which part of the specific immune response involves B lymphocytes?

B lymphocytes, or B cells, are involved in the humoral response of the specific immune response.

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What is the function of helper T cells?

Helper T cells bind to antigen-presenting cells and can form memory cells, stimulate B cells or phagocytes, and activate cytotoxic T cells.

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What is the role of cytotoxic T cells?

Cytotoxic T cells kill infected or abnormal cells.

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What is the cellular response?

The cellular response is the specific immune response that occurs when T cells respond to antigens presented on body cells.

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What are the different functions of cloned T cells?

  1. Develop into memory cells 
  2. Stimulate phagocytosis
  3. Stimulate division of B cells
  4. Activate cytotoxic T cells

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What are antigen-presenting cells

Antigen-presenting cells are cells (usually phagocytes) that display a pathogen's antigens on their cell surface.

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Describe the steps involved in the cellular response to pathogens. 

  1. Phagocytes engulf pathogens and display their antigens on the cell-surface. 
  2. Helper T cells with complementary receptors bind to these antigens
  3. This activates the T cell to divide by mitosis to form genetically identical clones. 
  4. These clones can carry out different functions. 

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