What are the hormone-producing cells in the pancreas, and what hormones do they produce?

  1. α cells in the islets of Langerhans - produce glucagon
  2. β cells in the islets of Langerhans - produce insulin

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What is the role of the liver in regulating blood glucose concentration?

The liver carries out the following to increase or decrease blood glucose concentration:

  1. Glycogenesis - the conversion of glucose into glycogen when blood glucose concentration is high
  2. Glycogenolysis - the breakdown of glycogen to glucose when blood glucose concentration is low
  3. Gluconeogenesis - the production of glucose from sources other than carbohydrates like fats and amino acids

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Why is it important to maintain a constant blood glucose concentration?

  1. Glucose is needed for respiration
  2. If blood glucose is too low or high it can cause osmotic problems in cells and even cell death

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What is the role of insulin in regulating blood glucose concentration?

Insulin lowers blood glucose concentration when it is too high by:

  1. Increasing the rate of glucose absorption into cells, especially muscle cells
  2. Increasing the rate of respiration
  3. Promoting glycogenesis
  4. Activating enzymes that convert glucose to glycogen and fat
  5. Decreasing gluconeogenesis
  6. Inhibiting the secretion of glucagon from α cells via negative feedback

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What is the role of glucagon in regulating blood glucose concentration?

Glucagon increases blood glucose concentration when it is too low by:

  1. Activating enzymes in liver cells that break down glycogen to glucose (glycogenolysis)
  2. Activating enzymes in liver cells that promote gluconeogenesis
  3. Inhibiting the secretion of insulin from β cells via negative feedback

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What is the role of adrenaline in regulating blood glucose level?

Adrenaline also increases blood glucose concentration when it is too low by:

  1. Activating enzymes in liver cells that break down glycogen to glucose (glycogenolysis)


Adrenaline can also activate enzymes in muscle cells that break down glycogen to glucose.

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