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Question 1
The table below shows some statements about different neurones. |
a) | Complete the table by placing a tick if the statement is true for each neurone and a cross if it is not true.
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b) | Describe three similarities between the structure of sensory and motor neurones.
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c) | Describe two differences between the structure of sensory and motor neurones.
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d) | Multiple sclerosis (MS) is a disease that causes the loss of myelin around motor neurones. Explain why the speed of nerve impulses is slower in people diagnosed with MS.
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Question 2
The statements below describe some of the events that take place during an action potential. A - Sodium ions diffuse into the axon. B - Potassium ions diffuse out of the axon. C - Potassium ion channels open. D - Sodium ion channels open. E - Active transport of sodium ions and potassium ions. |
a) | Which of the events, A to E, starts depolarisation?
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b) | Which of the events, A to E, starts repolarisation?
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c) | Sodium and potassium ions can only cross the cell membrane through proteins. Explain why.
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d) | Explain how a resting potential is established and maintained across the axon membrane of a neurone.
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Question 3
The diagram below shows how the voltage across the axon membrane changes during the generation and transmission of an action potential. |
a) | Which letters, A to F, show the point at which voltage-gated sodium ion channels are open?
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b) | Describe and explain what causes the change in membrane potential between points A and B.
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c) | Describe and explain what causes the change in membrane potential between points C and D.
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d) | Name period E on the diagram above and explain its importance in humans.
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Question 4
The diagram below shows a cross section through a myelinated neurone. |
a) | Name structures labelled A and B in the diagram above.
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b) | Name cell X shown in the diagram above.
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c) | Explain the importance of the myelin sheath in the transmission of action potentials.
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d) | Guillain-Barré syndrome is a very rare and serious condition affecting the myelin sheath of neurones. Patients diagnosed with Guillain-Barré syndrome often experience muscular weakness and muscular paralysis. Explain how damage to the myelin sheath may cause muscular paralysis.
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Question 5
The nervous system is made up of the central nervous system (CNS) and the peripheral nervous system (PNS). |
a) | Describe the roles of sensory receptor cells in the nervous system.
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b) | The central nervous system coordinates responses to changes in the environment. Explain how nervous impulses are transmitted to muscles to bring about a response.
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c) | The production of action potentials follows the all-or-nothing principle. Explain how this principle works.
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d) | Explain how the strength of a stimulus is communicated to the brain.
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Question 6
The diagram below shows the structure of a sensory neurone. |
a) | Name structures X, Y, and Z shown in the diagram above.
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b) | Describe how an action potential is generated in a sensory neurone.
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c) | The diagram below shows the changes in membrane potential of a receptor cell over a period of time.
Explain why stimulus 2 caused an action potential, but stimulus 1 did not.
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d) | The period between 2.8 and 3.6 ms is known as the refractory period. Describe what happens during the refractory period.
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Question 7
A group of scientists investigated the effect of length of time in an ice-cold water bath on the reaction times of mice. They used 30 mice and measured the reaction times after being placed in an ice-cold water bath for 0, 10, 20, and 30 seconds. Their results are shown below.
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a) | Suggest how the scientists would obtain results for 0 seconds.
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b) | Explain why a lower temperature results in slower nerve impulse transmission.
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c) | Nerve impulse conduction takes place faster across myelinated neurones than non-myelinated neurones. Explain why.
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d) | Give one factor, other than temperature and myelination, that increases the speed of nerve impulse conduction.
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