Question 1

Which level of organisation of a haemoglobin molecule is coded by a DNA molecule?

  A  

primary structure

  B  

secondary structure

  C  

tertiary structure

  D  

quaternary structure

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Question 2

The diagrams show the structures of two amino acids, each of which has two amine (–NH2) groups.

A peptide bond is formed between the two amino acids.

Which groups form the peptide bond?

  A  

1 and 4

  B  

1 and 5

  C  

2 and 6

  D  

3 and 5

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Question 3

Which statements about a peptide bond are correct?

1 - it joins two monomers that are always identical to each other

2 - it contains four different atoms

3 - it can be broken by the addition of water at room temperature

4 - it is important in the primary structure of proteins

  A  

1, 2, and 3

  B  

1 and 3 only

  C  

2, 3, and 4

  D  

2 and 4 only

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Question 4

Which statements about the primary structure of a protein are correct?

1 - it may be branched

2 - it is determined by the sequence of DNA bases

3 - it is unique to that protein

4 - it determines the tertiary structure of the protein

  A  

1, 2, and 3

  B  

1, 2, and 4

  C  

1, 3, and 4

  D  

2, 3, and 4

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Question 5

What could describe the tertiary structure of a protein?

1 - α-helix

2 - a globular structure

3 - the specific order of amino acids

4 - a specific three-dimensional (3D) shape

  A  

1, 2, and 3

  B  

1, 2, and 4

  C  

2 and 4 only

  D  

3 and 4 only

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Question 6

A conjugated protein is held together by many different types of bond.

Which bond is not formed when a conjugated protein folds into its quaternary structure?

  A  

disulphide

  B  

hydrogen

  C  

ionic


  D  

peptide


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Question 7

Which is the strongest type of bonding found in proteins?

  A  

disulfide bonds

  B  

hydrogen bonds

  C  

hydrophobic interactions

  D  

ionic bonds

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Question 8

Lysozyme is an enzyme found in tears and saliva.

Which statement refers only to the tertiary structure of lysozyme?

  A  

a section of the molecule consists of an α-helix

  B  

it consists of a single polypeptide

  C  

it is 129 amino acids long

  D  

the 35th and 52nd amino acids help form the active site

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Question 9

The diagram below is a chromatogram of three different amino acids. The distance travelled by the solvent from the baseline is 50 mm.

Using the information in the chromatogram, which option is the Rf value for the amino acid leucine (Leu)?

  A  

0.39

  B  

0.28

  C  

0.72

  D  

1.39

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Question 10

Which test would you use to confirm the presence of proteins in a solution?

  A  

Benedict's test

  B  

iodine test

  C  

biuret test

  D  

ethanol test

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